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1

Asthma

Papi, Alberto, Brightling, Christopher, Pedersen, Søren E, Reddel, Helen K

Journal:

Lancet (London, England)

Year:

2017

Language:

english

File:

PDF, 1.81 MB

english, 2017

2

FROM MOUNTAIN TO ICON

Goldie, Michelle H, Brightling, Chris E

Journal:

Near Eastern Archaeology

Year:

2011

Language:

english

File:

PDF, 1.55 MB

english, 2011

3

New and emerging drug treatments for severe asthma

Diver, S., Russell, R. J., Brightling, C.

Journal:

Clinical & Experimental Allergy

Year:

2018

Language:

english

File:

PDF, 519 KB

english, 2018

4

Cough Due to Asthma and Nonasthmatic Eosinophilic Bronchitis

Christopher E. Brightling

Journal:

Year:

2010

Language:

english

File:

PDF, 146 KB

english, 2010

5

Eosinophils, bronchitis and asthma: Pathogenesis of cough and airflow obstruction

C.E. Brightling

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 229 KB

english, 2011

6

Pathogenesis of asthma: implications for precision medicine

Russell, Richard J., Brightling, Christopher

Journal:

Clinical Science

Year:

2017

Language:

english

File:

PDF, 1.03 MB

english, 2017

7

Procalcitonin and C reactive protein in patients hospitalised with acute respiratory illness

Tristan Clark, Mona Bafadel, Carlene Reid, Marie-jo Medina, Michael Barer, Christopher Brightling, Karl Nicholson

Journal:

Journal of Infection

Year:

2010

Language:

english

File:

PDF, 70 KB

english, 2010

8

Eosinophilic bronchitis − what is it and why is it important?

Brightling, Pavord

Journal:

Clinical & Experimental Allergy

Year:

2000

Language:

english

File:

PDF, 45 KB

english, 2000

9

New insights into the role of the mast cell in asthma

C. E. Brightling, P. Bradding, I. D. Pavord, A. J. Wardlaw

Journal:

Clinical & Experimental Allergy

Year:

2003

Language:

english

File:

PDF, 139 KB

english, 2003

10

Maximize tube life by using internal and external inspection devices

Richard D. Roberts, John Brightling

Journal:

Process Safety Progress

Year:

2005

Language:

english

File:

PDF, 1.02 MB

english, 2005

11

Lung damage and airway remodelling in severe asthma

C. E. Brightling, S. Gupta, S. Gonem, S. Siddiqui

Journal:

Clinical & Experimental Allergy

Year:

2012

Language:

english

File:

PDF, 296 KB

english, 2012

12

Effects of antibiotic therapy at drying off on mastitis in the dry period and early lactation

JW BROWNING, GA MEIN, M. BARTON, TJ NICHOLLS, P. BRIGHTLING

Journal:

Australian Veterinary Journal

Year:

1990

Language:

english

File:

PDF, 397 KB

english, 1990

13

Mast cell infiltration of airway smooth muscle in asthma

Peter Bradding, Chris Brightling

Journal:

Respiratory Medicine

Year:

2007

Language:

english

File:

PDF, 126 KB

english, 2007

14

Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial

Christopher E Brightling, William Monteiro, Richard Ward, Debbie Parker, Michael DL Morgan, Andrew J Wardlaw, Ian D Pavord

Journal:

Year:

2000

Language:

english

File:

PDF, 103 KB

english, 2000

15

Mast-Cell Infiltration of Airway Smooth Muscle in Asthma

Brightling, Christopher E., Bradding, Peter, Symon, Fiona A., Holgate, Stephen T., Wardlaw, Andrew J., Pavord, Ian D.

Journal:

Boston Medical and Surgical Journal

Year:

2002

Language:

english

File:

PDF, 126 KB

english, 2002

16

Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study

Brightling, Christopher E, Bleecker, Eugene R, Panettieri, Reynold A, Bafadhel, Mona, She, Dewei, Ward, Christine K, Xu, Xiao, Birrell, Claire, van der Merwe, René

Journal:

The Lancet Respiratory Medicine

Year:

2014

Language:

english

File:

PDF, 812 KB

english, 2014

17

Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease

Brightling, C E

Journal:

Year:

2005

Language:

english

File:

PDF, 128 KB

english, 2005

18

Dedicated Severe Asthma Services Improve Health-care Use and Quality of Life

Gibeon, David, Heaney, Liam G., Brightling, Chris E., Niven, Rob, Mansur, Adel H., Chaudhuri, Rekha, Bucknall, Christine E., Menzies-Gow, Andrew N.

Journal:

Year:

2015

Language:

english

File:

PDF, 197 KB

english, 2015

19

Blood eosinophils and outcomes in severe hospitalised exacerbations of COPD

Bafadhel, Mona, Greening, Neil J., Harvey-Dunstan, Theresa C., Williams, Johanna E.A., Morgan, Michael D., Brightling, Christopher E., Hussain, Syed F., Pavord, Ian D., Singh, Sally J., Steiner, Micha

Journal:

Year:

2016

Language:

english

File:

PDF, 485 KB

english, 2016

20

[American Thoracic Society American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans - ()] A41. CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATIONS: EPIDEMIOLOGY AND OUTCOMES - The Role Of A Peripheral Blood Eosinophil Count As A Biomarker For A Sputum Eosinophilia In COPD Exacerbations

Bafadhel, Mona, Terry, Sarah, McKenna, Susan, Mistry, Vijay, Reid, Carlene, McCormick, Margaret, Dodson, Paul, Rugman, Paul, Jenkins, Martin, Saunders, Michael, Pavord, Ian D., Brightling, Christopher

Year:

2010

Language:

english

File:

PDF, 20 KB

english, 2010

21

Clinical trial research in focus: do trials prepare us to deliver precision medicine in those with severe asthma?

Brightling, Christopher E

Journal:

The Lancet Respiratory Medicine

Year:

2017

Language:

english

File:

PDF, 116 KB

english, 2017

22

[American Thoracic Society American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California - ()] A38. COPD: DIAGNOSIS & EVALUATION - The Sensitivity and Specificity of Peripheral Blood Eosinophilia To Predict Sputum Eosinophilia in COPD Subjects.

Bafadhel, M, McKenna, S, Pickering, S, Reid, C, Mistry, V, Rugman, P, Saunders, M, Brightling, CE

Year:

2009

Language:

english

File:

PDF, 117 KB

english, 2009

23

Biologic Drugs: A New Target Therapy in COPD?

Yousuf, Ahmed, Brightling, Christopher E

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2018

Language:

english

File:

PDF, 835 KB

english, 2018

24

Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebo-controlled, phase 3 clinical trials

Panettieri, Reynold A, Sjöbring, Ulf, Péterffy, AnnaMaria, Wessman, Peter, Bowen, Karin, Piper, Edward, Colice, Gene, Brightling, Christopher E

Journal:

The Lancet Respiratory Medicine

Year:

2018

Language:

english

File:

PDF, 412 KB

english, 2018

25

Benralizumab for the Prevention of COPD Exacerbations

Criner, Gerard J., Celli, Bartolome R., Brightling, Christopher E., Agusti, Alvar, Papi, Alberto, Singh, Dave, Sin, Don D., Vogelmeier, Claus F., Sciurba, Frank C., Bafadhel, Mona, Backer, Vibeke, Kat

Journal:

New England Journal of Medicine

Year:

2019

Language:

english

File:

PDF, 286 KB

english, 2019

26

Cough and Eosinophilia

Diver, Sarah, Russell, Richard J., Brightling, Christopher E.

Journal:

The Journal of Allergy and Clinical Immunology: In Practice

Year:

2019

Language:

english

File:

PDF, 1.25 MB

english, 2019

27

Sputum microbiome profiling in COPD: beyond singular pathogen detection

Ditz, Benedikt, Christenson, Stephanie, Rossen, John, Brightling, Chris, Kerstjens, Huib A M, van den Berge, Maarten, Faiz, Alen

Journal:

Year:

2020

Language:

english

File:

PDF, 446 KB

english, 2020

28

Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor

S. Mark Duffy, Glenn Cruse, Christopher E. Brightling, Peter Bradding

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 466 KB

english, 2007

29

Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migration

S. Mark Duffy, Glenn Cruse, Sarah L. Cockerill, Chris E. Brightling, Peter Bradding

Journal:

European Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 199 KB

english, 2008

30

Rolling-sliding dry wear testing — A vibration analysis

J.E. Garnham, J.R. Brightling, J.H. Beynon

Journal:

Year:

1988

Language:

english

File:

PDF, 1.44 MB

english, 1988

31

The role of the mast cell in asthma. Response to A. M. Edwards by C. Brightling, P. Bradding

C. Brightling, P. Bradding

Journal:

Clinical & Experimental Allergy

Year:

2003

Language:

english

File:

PDF, 51 KB

english, 2003

32

Cough and asthma

M. A. Berry, S. S. Birring, C. E. Brightling, I. D. Pavord

Journal:

Clinical & Experimental Allergy

Year:

2003

Language:

english

File:

PDF, 221 KB

english, 2003

33

IL-13 expression by blood T cells and not eosinophils is increased in asthma compared to non-asthmatic eosinophilic bronchitis

Salman Siddiqui, Glenn Cruse, Susan Mckenna, William Monteiro, Vijay Mistry, Andrew Wardlaw, Christopher Brightling

Journal:

BMC Pulmonary Medicine

Year:

2009

Language:

english

File:

PDF, 1.56 MB

english, 2009

34

Airways Disease: Phenotyping Heterogeneity Using Measures of Airway Inflammation

Salman Siddiqui, Christopher E Brightling

Journal:

Allergy, Asthma & Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 499 KB

english, 2007

35

The utility of the mannitol challenge in the assessment of chronic cough: a pilot study

Amisha Singapuri, Susan McKenna, Christopher E Brightling

Journal:

Year:

2008

Language:

english

File:

PDF, 633 KB

english, 2008

36

Sputum eosinophilia in idiopathic pulmonary fibrosis

S. S. Birring, D. Parker, S. McKenna, B. Hargadon, C. E. Brightling, I. D. Pavord, P. Bradding

Journal:

Inflammation Research

Year:

2005

Language:

english

File:

PDF, 127 KB

english, 2005

37

The re-emergence of the mast cell as a pivotal cell in asthma pathogenesis

Christopher E. Brightling, Peter Bradding

Journal:

Current Allergy and Asthma Reports

Year:

2005

Language:

english

File:

PDF, 501 KB

english, 2005

38

Interleukin-4 and -13 expression is co-localized to mast cells within the airway smooth muscle in asthma

C. E. Brightling, F. A. Symon, S. T. Holgate, A. J. Wardlaw, I. D. Pavord, P. Bradding

Journal:

Clinical & Experimental Allergy

Year:

2003

Language:

english

File:

PDF, 2.18 MB

english, 2003

39

Observational study of the natural history of eosinophilic bronchitis

M. A. Berry, B. Hargadon, S. McKenna, D. Shaw, R. H. Green, C. E. Brightling, A. J. Wardlaw, I. D. Pavord

Journal:

Clinical & Experimental Allergy

Year:

2005

Language:

english

File:

PDF, 94 KB

english, 2005

40

Co-cultivation of mast cells and FcɛRIα+ dendritic-like cells from human hip bone marrow

D. Kaur, P. Berger, S. M. Duffy, C. E. Brightling, P. Bradding

Journal:

Clinical & Experimental Allergy

Year:

2005

Language:

english

File:

PDF, 1.41 MB

english, 2005

41

The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma

M. A. Berry, D. E. Shaw, R. H. Green, C. E. Brightling, A. J. Wardlaw, I. D. Pavord

Journal:

Clinical & Experimental Allergy

Year:

2005

Language:

english

File:

PDF, 116 KB

english, 2005

42

Airway smooth muscle chemokine receptor expression and function in asthma

R. Saunders, A. Sutcliffe, D. Kaur, S. Siddiqui, F. Hollins, A. Wardlaw, P. Bradding, C. Brightling

Journal:

Clinical & Experimental Allergy

Year:

2009

Language:

english

File:

PDF, 310 KB

english, 2009

43

Interleukin-13: prospects for new treatments

C. E. Brightling, S. Saha, F. Hollins

Journal:

Clinical & Experimental Allergy

Year:

2010

Language:

english

File:

PDF, 237 KB

english, 2010

44

Severe asthma: a consequence of over exuberant repair?

C. E. Brightling, D. Desai, S. Siddiqui

Journal:

Clinical & Experimental Allergy

Year:

2009

Language:

english

File:

PDF, 60 KB

english, 2009

45

Airway smooth muscle proliferation and survival is not modulated by mast cells

D. Kaur, F. Hollins, R. Saunders, L. Woodman, A. Sutcliffe, G. Cruse, P. Bradding, C. Brightling

Journal:

Clinical & Experimental Allergy

Year:

2010

Language:

english

File:

PDF, 344 KB

english, 2010

46

Expression of CCR8 is increased in asthma

K. Mutalithas, C. Guillen, C. Raport, R. Kolbeck, D. Soler, C. E. Brightling, I. D. Pavord, A. J. Wardlaw

Journal:

Clinical & Experimental Allergy

Year:

2010

Language:

english

File:

PDF, 697 KB

english, 2010

47

Cytokine and anti-cytokine therapy in asthma: ready for the clinic?

D. Desai, C. Brightling

Journal:

Clinical & Experimental Immunology

Year:

2009

Language:

english

File:

PDF, 210 KB

english, 2009

48

CRTH2 expression on T cells in asthma

K. Mutalithas, C. Guillen, C. Day, C. E. Brightling, I. D. Pavord, A. J. Wardlaw

Journal:

Clinical & Experimental Immunology

Year:

2010

Language:

english

File:

PDF, 283 KB

english, 2010

49

Mast cells express IL-13Rα1: IL-13 promotes human lung mast cell proliferation and FcɛRI expression

D. Kaur, F. Hollins, L. Woodman, W. Yang, P. Monk, R. May, P. Bradding, C. E. Brightling

Journal:

Year:

2006

Language:

english

File:

PDF, 217 KB

english, 2006

50

The airway smooth muscle CCR3/CCL11 axis is inhibited by mast cells

R. Saunders, A. Sutcliffe, L. Woodman, D. Kaur, S. Siddiqui, Y. Okayama, A. Wardlaw, P. Bradding, C. Brightling

Journal:

Year:

2008

Language:

english

File:

PDF, 380 KB

english, 2008

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